Revisiting the role of neurotransmitters in epilepsy: An updated review

E Akyuz, AK Polat, E Eroglu, I Kullu, E Angelopoulou… - Life sciences, 2021 - Elsevier
… With this study, the glutamate receptors specified contribute to the FR … and contributes
to epileptic activity. TNF-α induces … the genetic absence epilepsy in rats from Strasbourg (GAERS) …

[HTML][HTML] Targeting gap junction in epilepsy: Perspectives and challenges

Q Li, QQ Li, JN Jia, ZQ Liu, HH Zhou, XY Mao - Biomedicine & …, 2019 - Elsevier
glutamate as a result of astrocytic uncoupling is expected to generate and sustain spontaneous
epileptiform activity… of spontaneous epileptiform activity in rat hippocampal slices [136]. …

Group I metabotropic glutamate receptors contribute to the antiepileptic effect of electrical stimulation in hippocampal CA1 pyramidal neurons

Z Ghasemi, N Naderi, A Shojaei, MR Raoufy… - Epilepsy Research, 2021 - Elsevier
glutamate receptors group I (mGluR I) in LFS inhibitory action on epileptiform activity (EA) …
fluid (ACSF) up to 12 mM in hippocampal slices of male Wistar rats. LFS (1 Hz, 900 pulses) …

The role of α adrenergic receptors in mediating the inhibitory effect of electrical brain stimulation on epileptiform activity in rat hippocampal slices

N Ahmadirad, Y Fathollahi, M Janahmadi, Z Ghasemi… - Brain Research, 2021 - Elsevier
… This will help the clinicians to … receptors on glutamatergic transmission. There are many
reports showing that activation of α adrenergic receptors leads to suppression of glutamatergic

[HTML][HTML] Questioning glutamate excitotoxicity in acute brain damage: the importance of spreading depolarization

RD Andrew, E Farkas, JA Hartings, KC Brennan… - Neurocritical care, 2022 - Springer
glutamate application to naïve slices. No SD was observed in … The effect is less obvious
in neocortical slices, where SD … So, although reversed glutamate transport may contribute to …

MWCNTs/PEDOT: PSS nanocomposites-modified microelectrode array for spatial dynamics recording of epileptic discharges in multi-subregion of hippocampal slice

E He, S Xu, G Xiao, Y Dai, X Li, Y Song, F Gao… - Sensors and Actuators B …, 2021 - Elsevier
… MEA for rat hippocampal slices to study the origin and spread of … The lines and letters on the
MEA help position the slice into the … of glutamate receptors that affect the spread of epileptic

[HTML][HTML] The effect of anti-seizure medications on the propagation of epileptic activity: a review

M Khateb, N Bosak, M Herskovitz - Frontiers in Neurology, 2021 - frontiersin.org
… , the spread of epileptiform activities in neocortical slices was … models, including rat amygdala
kindling and rat pilocarpine models, … calcium channel reducing glutamate release in critical …

[HTML][HTML] Astrocytic connexin43 channels as candidate targets in epilepsy treatment

L Walrave, M Vinken, L Leybaert, I Smolders - Biomolecules, 2020 - mdpi.com
… redistribution of K + and glutamate and display a higher … slices developed spontaneous
epileptiform activity and only … -like events in bicuculline-treated neocortical slices [160]. However, …

[HTML][HTML] … electrode array for epileptiform electrical activity recording under glutamate and GABA modulation on the primary somatosensory cortex of rats

X Li, Y Song, G Xiao, J Xie, Y Dai, Y Xing, E He… - Micromachines, 2020 - mdpi.com
… fabricated to detect epileptiform activity under glutamate (Glu) … pad area was stuck to a PI
thin slice (0.3 mm total thickness) … activity between normal and epileptiform states help to detect …

Cortical spreading depression: culprits and mechanisms

AA Mathew, R Panonnummal - Experimental brain research, 2022 - Springer
… using chick retina and neocortical slices. Induction of CSD in … releases glutamine and activates
glutamatergic transmission… the rat neocortex that dopamine can acts on the D2 receptors